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Digestive Enzymes: What They Are & How They Work

Digestive Enzymes: What They Are & How They Work

Even the most perfectly balanced diet won't help if your body cannot properly process the food it receives. Processing begins with digestion—the ability of the human body to break down food into nutrients that can be absorbed. Solid food alone cannot deliver vitamins and minerals; this becomes possible only when food undergoes transformation. And this transformation is made possible exclusively by digestive enzymes, which initiate the conversion of food into absorbable compounds.

What Are Digestive Enzymes?

Digestive enzymes, broadly speaking, are a group of enzymes secreted throughout the digestive system. In reality, this encompasses many different enzymes, each responsible for catalysing the breakdown of specific complex compounds into simpler ones. Some enzymes focus on breaking down proteins into amino acids, while others target carbohydrates, fats, and other substances.

These enzymes are produced naturally in the body by digestive glands. However, the quantity produced isn't always sufficient for optimal bodily function. The digestive process actually begins in the oral cavity, where salivary glands produce the first digestive enzymes. From there, the task of breaking down food is taken over by enzymes produced in the stomach and intestines, as well as by other organs—notably the pancreas.

[tip:Chewing your food thoroughly is the first step in good digestion. It not only mechanically breaks down food but also gives salivary enzymes (like amylase) more time to begin carbohydrate digestion before food reaches the stomach.]

The Role of Digestive Enzymes

The human body produces most of the digestive enzymes necessary for proper function. Their role comes down to two main functions:

Breaking down food into absorbable nutrients. The most well-known digestive enzymes include:

  • Amylase – facilitates the breakdown of starches into simple sugars
  • Lipase – supports the breakdown of fats into fatty acids and glycerol
  • Protease – specialised in breaking down proteins into amino acids
  • Lactase – breaks down milk sugar (lactose) into glucose and galactose
  • Cellulase – helps break down plant fibre

Metabolic enzymes then take over the process. Their task is to facilitate the utilisation of nutrients at the cellular level, converting them into energy and building materials for the body.

Maintaining proper enzyme levels in the body is the only guarantee of digestive system health and the correct functioning of digestive processes.

Lactase: The Enzyme for Lactose Digestion

Lactose intolerance is caused by the inability to properly digest lactose due to insufficient amounts of the enzyme lactase. This enzyme is produced in the brush border of the small intestine epithelium and participates in the hydrolysis of lactose into simple sugars—glucose and galactose—which are more easily absorbed by the body.

When lactase is deficient, symptoms of lactose intolerance appear, including:

  • Diarrhoea
  • Bloating
  • Abdominal pain
  • Excessive intestinal gas production

Thanks to supplements containing the lactase enzyme, it's possible to counteract these symptoms and spare those with intolerance from having to completely eliminate dairy products. Typically, taking one tablet before each meal containing milk or dairy products is sufficient to avoid unpleasant digestive discomfort.

[note:Lactose intolerance is different from milk allergy. Intolerance is an enzyme deficiency affecting digestion, while allergy is an immune response to milk proteins. Lactase supplements help with intolerance but not with allergy.]

Digestive Enzymes for Reflux

Reflux is the backward flow of stomach contents from the stomach into the oesophagus. This condition is most commonly accompanied by a burning sensation in the area around the breastbone. Reflux is caused by improper stomach function, which leads to incomplete closure of the lower oesophageal sphincter, allowing stomach contents to escape upward.

To help prevent this, it's necessary to maintain the proper composition of digestive juices, which include the enzyme pepsinogen. Pepsinogen, together with hydrochloric acid, is converted into pepsin, which digests proteins, fats, and sugars. Pepsin can also be taken externally in tablet form, often combined with Betaine HCL, which helps regulate stomach acidity.

For those with insufficient stomach acid (hypochlorhydria), Betaine HCL with pepsin can support proper protein digestion and may help reduce symptoms associated with incomplete digestion.

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Signs of Digestive Enzyme Deficiency

Digestive enzyme deficiency is a serious matter that shouldn't be ignored, as it can lead to significant health problems. The main issue is that initially, enzyme deficiency causes many unpleasant symptoms, but these are often temporary, so they don't receive much attention.

However, it's worth investigating your enzyme levels if you experience some of the following symptoms:

  • Constant hunger despite eating adequate meals
  • Irritability and mood changes
  • Rapid weight gain
  • Persistent fatigue
  • Muscle cramps
  • Bloating after meals
  • Chronic constipation
  • Frequent Candida infections
  • Colitis or intestinal inflammation
  • Slow, improper digestion

Taking immediate action can help avoid serious health consequences. Chronic deficiency can lead to significant digestive and metabolic disorders, ultimately resulting in improper bodily function.

[warning:If you experience persistent digestive symptoms, consult a healthcare professional. Enzyme deficiency can sometimes indicate underlying conditions affecting the liver, gallbladder, or pancreas that require medical attention.]

Replenishing Digestive Enzymes

Digestive enzyme deficiency can be addressed, but first it's important to understand its cause. It may result from dysfunction of the liver, gallbladder, or small intestine—in such cases, a visit to a doctor is essential.

However, enzyme deficiency very often results from an inadequate diet or toxin accumulation. Age can also be a factor, as enzyme production naturally decreases over the years. In these situations, help comes from:

Dietary Changes

Changing eating habits, creating a more balanced diet, and consuming foods that support digestion can make a significant difference. Enzyme-rich foods include:

  • Pineapple – contains bromelain, which aids protein digestion
  • Papaya – rich in papain, another powerful proteolytic enzyme
  • Raw vegetables and fruits – contain natural enzymes (cooking destroys them)
  • Fermented foods – sauerkraut, kimchi, kefir support digestive health
  • Legumes – provide fibre that supports gut bacteria

Cleansing and Detoxification

Body cleansing and detoxification should be the next step in treatment. This will restore proper liver and pancreatic function and help regain balance in the intestinal microflora, which plays a direct role in enzyme production.

External Supplementation

Supplementation with probiotics and digestive enzymes can restore wellbeing and healthy appearance. Enzyme supplements are particularly helpful during periods of digestive stress, when eating unfamiliar foods, or as we age and natural enzyme production declines.

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Choosing the Right Enzyme Supplement

When selecting a digestive enzyme supplement, consider your specific needs:

  • Broad-spectrum enzymes – ideal for general digestive support and mixed meals
  • Betaine HCL with pepsin – for those with low stomach acid or protein digestion issues
  • Lactase – specifically for lactose intolerance
  • Plant-based enzymes – suitable for vegetarians and those preferring non-animal sources
  • Enzyme-probiotic combinations – for comprehensive gut health support

Most digestive enzyme supplements are taken with meals for optimal effect. Some, like Betaine HCL, are best taken at the beginning of a meal, while others can be taken before or during eating.

Key Takeaway: Digestive enzymes are essential catalysts that transform food into absorbable nutrients. Without adequate enzyme levels, even the healthiest diet cannot provide full benefits. If you experience digestive discomfort, enzyme supplementation—combined with dietary improvements and gut health support—can help restore optimal digestive function and overall wellbeing.

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